Light induced apoptosis is accelerated in transgenic retina overexpressing human EAT/mcl-1, an anti-apoptotic bcl-2 related gene

BACKGROUND/AIM—EAT/mcl-1 (EAT), an immediate early gene, functions in a similar way to bcl-2 in neutralising Bax mediated cytotoxicity, suggesting that EAT is a blocker of cell death. The aim of this study was to determine the effect of overexpression of the human EAT gene on light induced retinal c...

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Detalhes bibliográficos
Main Authors: Shinoda, K., Nakamura, Y., Matsushita, K., Shimoda, K., Okita, H., Fukuma, M., Yamada, T., Ohde, H., Oguchi, Y., Hata, J., Umezawa, A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Original articles - Laboratory science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1723738/
https://ncbi.nlm.nih.gov/pubmed/11567971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bjo.85.10.1237
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