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Regulation of anti-apoptotic Bcl-2 family protein Mcl-1 by S6 kinase 2

The anti-apoptotic Bcl-2 family protein myeloid cell leukemia-1 (Mcl-1) plays an important role in breast cancer cell survival and chemoresistance. We have previously shown that knockdown of the 40S ribosomal protein S6 kinase-2 (S6K2), which acts downstream of the mechanistic target of rapamycin co...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Basu, Alakananda, Sridharan, Savitha
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354308/
https://ncbi.nlm.nih.gov/pubmed/28301598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173854
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