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S6 Kinase2 Promotes Breast Cancer Cell Survival via Akt

The 40S ribosomal protein S6 kinase (S6K) acts downstream of the mammalian target of rapamycin (mTOR), which plays important roles in cell proliferation, protein translation and cell survival and is a target for cancer therapy. mTOR inhibitors are, however, of limited success. Although Akt is believ...

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Detalhes bibliográficos
Main Authors: Sridharan, Savitha, Basu, Alakananda
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070841/
https://ncbi.nlm.nih.gov/pubmed/21427355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3253
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