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Distinct Roles of mTOR Targets S6K1 and S6K2 in Breast Cancer

The mechanistic target of rapamycin (mTOR) is a master regulator of protein translation, metabolism, cell growth and proliferation. It forms two complexes, mTOR complex 1 (mTORC1) and 2 (mTORC2). mTORC1 is frequently deregulated in many cancers, including breast cancer, and is an important target fo...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Sridharan, Savitha, Basu, Alakananda
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072743/
https://ncbi.nlm.nih.gov/pubmed/32054043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21041199
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