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mTOR function and therapeutic targeting in breast cancer
The mTOR pathway was discovered in the late 1970s after the compound and natural inhibitor of mTOR, rapamycin was isolated from the bacterium Streptomyces hygroscopicus. mTOR is serine/threonine kinase belonging to the phosphoinositide 3-kinase related kinase (PIKK) family. It forms two distinct com...
Tallennettuna:
| Julkaisussa: | Am J Cancer Res |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
e-Century Publishing Corporation
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5385631/ https://ncbi.nlm.nih.gov/pubmed/28400999 |
| Tagit: |
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