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Brainstem Alzheimer’s-Like Pathology in the Triple Transgenic Mouse Model of Alzheimer’s Disease
The triple transgenic mouse (3xTgAD), harboring human APP(Swe), PS1(M146V) and Tau(P301L) genes, develops age-dependent forebrain intraneuronal Aβ and tau and extraneuronal plaques. We evaluated brainstem AD-like pathology using 6E10, AT8, and Alz50 antibodies and unbiased stereology in young and ol...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3085918/ https://ncbi.nlm.nih.gov/pubmed/19524671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.06.004 |
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