The flavonoid, 2′-methoxy-6-methylflavone, affords neuroprotection following focal cerebral ischaemia

Tonic inhibitory currents, mediated by extrasynaptic GABA(A) receptors, are elevated at a delay following stroke. Flavonoids minimise the extent of cellular damage following stroke, but little is known about their mode of action. We demonstrate that the flavonoid, 2′-methoxy-6-methylflavone (0.1–10 ...

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Publicat a:J Cereb Blood Flow Metab
Autors principals: Clarkson, Andrew N, Boothman-Burrell, Lily, Dósa, Zita, Nagaraja, Raghavendra Y, Jin, Liang, Parker, Kim, van Nieuwenhuijzen, Petra S, Neumann, Silke, Gowing, Emma K, Gavande, Navnath, Ahring, Philip K, Holm, Mai M, Hanrahan, Jane R, Nicolazzo, Joseph A, Jensen, Kimmo, Chebib, Mary
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668512/
https://ncbi.nlm.nih.gov/pubmed/29376464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0271678X18755628
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