Aβ Immunotherapy: Intracerebral Sequestration of Aβ by an Anti-Aβ Monoclonal Antibody 266 with High Affinity to Soluble Aβ

Amyloid β (Aβ) immunotherapy is emerging as a promising disease-modifying therapy for Alzheimer's disease, although the precise mechanisms whereby anti-Aβ antibodies act against amyloid deposition and cognitive deficits remain elusive. To test the “peripheral sink” theory, which postulates that...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Yamada, Kaoru, Yabuki, Chiori, Seubert, Peter, Schenk, Dale, Hori, Yukiko, Ohtsuki, Sumio, Terasaki, Tetsuya, Hashimoto, Tadafumi, Iwatsubo, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665926/
https://ncbi.nlm.nih.gov/pubmed/19741145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2021-09.2009
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