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Brain-to-Blood Transporters for Endogenous Substrates and Xenobiotics at the Blood-Brain Barrier: An Overview of Biology and Methodology

Summary: In the past decade, research into P-glycoprotein involving the blood-brain barrier (BBB) has seen a shift in the concept of the BBB as a structural barrier to that of a functional barrier for xenobiotics and changed simultaneously the strategy for the discovery and development of drugs acti...

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Detalhes bibliográficos
Main Authors: Terasaki, Tetsuya, Ohtsuki, Sumio
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Experimental NeuroTherapeutics, Inc. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539321/
https://ncbi.nlm.nih.gov/pubmed/15717058
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