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Mouse embryonic palatal mesenchymal cells maintain stemness through the PTEN-Akt-mTOR autophagic pathway

BACKGROUND: Both genetic and environmental factors are implicated in the pathogenesis of cleft palate. However, the molecular and cellular mechanisms that regulate the development of palatal shelves, which are composed of mesenchymal cells, have not yet been fully elucidated. This study aimed to det...

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Библиографические подробности
Опубликовано в: :Stem Cell Res Ther
Главные авторы: Shi, Lungang, Li, Binchen, Zhang, Binna, Zhen, Congyuan, Zhou, Jianda, Tang, Shijie
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664599/
https://ncbi.nlm.nih.gov/pubmed/31358051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1340-8
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