Crocin induces autophagic apoptosis in hepatocellular carcinoma by inhibiting Akt/mTOR activity

BACKGROUND: Autophagy induction is a common mechanism for antitumor chemicals in induction of cancer cell death. However, the role of autophagy in crocin-induced apoptosis is barely studied in hepatocellular carcinoma (HCC). MATERIALS AND METHODS: The influence of crocin on growth, apoptosis, and au...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Onco Targets Ther
Main Authors: Yao, Chong, Liu, Bing-Bing, Qian, Xiao-Dong, Li, Li-Qin, Cao, Heng-Bin, Guo, Qiao-Sheng, Zhou, Gui-Fen
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2018
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5898595/
https://ncbi.nlm.nih.gov/pubmed/29670377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S154586
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