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PRAS40 alleviates neurotoxic prion peptide‐induced apoptosis via mTOR‐AKT signaling
AIMS: The proline‐rich Akt substrate of 40‐kDa (PRAS40) protein is a direct inhibitor of mTORC1 and an interactive linker between the Akt and mTOR pathways. The mammalian target of rapamycin (mTOR) is considered to be a central regulator of cell growth and metabolism. Several investigations have dem...
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| Gepubliceerd in: | CNS Neurosci Ther |
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| Hoofdauteurs: | , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6492730/ https://ncbi.nlm.nih.gov/pubmed/28294542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.12685 |
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