PRAS40 plays a pivotal role in protecting against stroke by linking the Akt and mTOR pathways

The proline-rich Akt substrate of 40 kDa (PRAS40) protein is not only a substrate of the protein kinase Akt but also a component of the mTOR complex 1 (mTORC1), thus it links the Akt and the mTOR pathways. We investigated the potential protective role of PRAS40 in cerebral ischemia and its underlyin...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Xiong, Xiaoxing, Xie, Rong, Zhang, Hongfei, Gu, Lijuan, Xie, Weiying, Cheng, Michelle, Jian, Zhihong, Kovacina, Kristina, Zhao, Heng
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448971/
https://ncbi.nlm.nih.gov/pubmed/24583056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.02.006
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