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CD4 T cell deficiency attenuates ischemic stroke, inhibits oxidative stress, and enhances Akt/mTOR survival signaling pathways in mice

BACKGROUND: Inhibition of CD4 T cells reduces stroke-induced infarction by inhibiting neuroinflammation in the ischemic brain in experimental stroke. Nevertheless, little is known about its effects on neuronal survival signaling pathways. In this study, we investigated the effects of CD4 T cell defi...

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Bibliografiske detaljer
Udgivet i:Chin Neurosurg J
Main Authors: Zhang, Hongfei, Xiong, Xiaoxing, Gu, Lijuan, Xie, Weiying, Zhao, Heng
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398241/
https://ncbi.nlm.nih.gov/pubmed/32832192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41016-018-0140-9
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