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Akt isoforms differentially protect against stroke-induced neuronal injury by regulating mTOR activities
Protein kinases Akt1 and Akt3 are considered to be more crucial to brain function than Akt2. We investigated the roles of Akt1 and Akt3 in stroke-induced brain injury and examined their interactions with the Akt/mTOR pathways. Focal ischemia was induced in rats. Lentiviral vectors expressing constit...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3851893/ https://ncbi.nlm.nih.gov/pubmed/23942361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.132 |
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