YAP manipulates proliferation via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas

BACKGROUND: Autophagy is a double-edged sword during the initiation and progression of multiple tumors. The Hippo pathway effector YAP has been proved to be involved in autophagy processes. The present study aimed to investigate how YAP regulates cell proliferation via autophagy in lung adenocarcino...

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Gepubliceerd in:Cancer Cell Int
Hoofdauteurs: Xu, Wei, Zhang, Mingjiong, Li, Yue, Wang, Yu, Wang, Kai, Chen, Qiaoyu, Zhang, Runjie, Song, Weiwei, Huang, Qiqing, Zhao, Weihong, Wu, Jianqing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791871/
https://ncbi.nlm.nih.gov/pubmed/33413409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01688-9
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