YAP manipulates proliferation via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas

BACKGROUND: Autophagy is a double-edged sword during the initiation and progression of multiple tumors. The Hippo pathway effector YAP has been proved to be involved in autophagy processes. The present study aimed to investigate how YAP regulates cell proliferation via autophagy in lung adenocarcino...

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Veröffentlicht in:Cancer Cell Int
Hauptverfasser: Xu, Wei, Zhang, Mingjiong, Li, Yue, Wang, Yu, Wang, Kai, Chen, Qiaoyu, Zhang, Runjie, Song, Weiwei, Huang, Qiqing, Zhao, Weihong, Wu, Jianqing
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7791871/
https://ncbi.nlm.nih.gov/pubmed/33413409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01688-9
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