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Metformin mediates neuroprotection and attenuates hearing loss in experimental pneumococcal meningitis

BACKGROUND: Pneumococcal meningitis is associated with high risk of neurological sequelae such as cognitive impairment and hearing loss. These sequelae are due to parenchymal brain and inner ear damage primarily induced by the excessive inflammatory reaction in response to bacterial brain invasion....

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Muri, Lukas, Le, Ngoc Dung, Zemp, Jonas, Grandgirard, Denis, Leib, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660697/
https://ncbi.nlm.nih.gov/pubmed/31351490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1549-6
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