Evaluation of neurofilament light chain in the cerebrospinal fluid and blood as a biomarker for neuronal damage in experimental pneumococcal meningitis

BACKGROUND: Pneumococcal meningitis (PM) remains a global public health concern and affects all age groups. If acquired during infancy or childhood, permanent neurofunctional deficits including cognitive impairment, cerebral palsy, and secondary epilepsy are typical sequelae of neuronal injury. Dete...

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Pubblicato in:J Neuroinflammation
Autori principali: Le, Ngoc Dung, Muri, Lukas, Grandgirard, Denis, Kuhle, Jens, Leppert, David, Leib, Stephen L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7539528/
https://ncbi.nlm.nih.gov/pubmed/33028339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01966-3
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