Attenuation of Cerebrospinal Fluid Inflammation by the Nonbacteriolytic Antibiotic Daptomycin versus That by Ceftriaxone in Experimental Pneumococcal Meningitis

Antibiotic-induced bacteriolysis exacerbates inflammation and brain damage in bacterial meningitis. Here the quality and temporal kinetics of cerebrospinal fluid (CSF) inflammation were assessed in an infant rat pneumococcal meningitis model for the nonbacteriolytic antibiotic daptomycin versus ceft...

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Bibliografiske detaljer
Main Authors: Grandgirard, Denis, Oberson, Kevin, Bühlmann, Angela, Gäumann, Rahel, Leib, Stephen L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825988/
https://ncbi.nlm.nih.gov/pubmed/20065062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00812-09
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