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HNRNPA1-mediated 3′ UTR length changes of HN1 contributes to cancer- and senescence-associated phenotypes

Cellular senescence has been regarded as a mechanism of tumor suppression. Studying the regulation of gene expression at various levels in cell senescence will shed light on cancer therapy. Alternative polyadenylation (APA) regulates gene expression by altering 3′ untranslated regions (3′ UTR) and p...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Principais autores: Jia, Qi, Nie, Hongbo, Yu, Peng, Xie, Baiyun, Wang, Chenji, Yang, Fu, Wei, Gang, Ni, Ting
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660030/
https://ncbi.nlm.nih.gov/pubmed/31257225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102060
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