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The Splicing Factor hnRNPA1 Regulates Alternate Splicing of the MYLK Gene

Profound lung vascular permeability is a cardinal feature of acute respiratory distress syndrome (ARDS) and ventilator-induced lung injury (VILI), two syndromes known to centrally involve the nonmuscle isoform of myosin light chain kinase (nmMLCK) in vascular barrier dysregulation. Two main splice v...

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Pubblicato in:Am J Respir Cell Mol Biol
Autori principali: Mascarenhas, Joseph B., Tchourbanov, Alex Y., Danilov, Sergei M., Zhou, Tong, Wang, Ting, Garcia, Joe G. N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Thoracic Society 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946327/
https://ncbi.nlm.nih.gov/pubmed/29077485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0141OC
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