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Mechanical Stress and Single Nucleotide Variants Regulate Alternative Splicing of the MYLK Gene
The nonmuscle (nm) myosin light-chain kinase isoform (MLCK), encoded by the MYLK gene, is a vital participant in regulating vascular barrier responses to mechanical and inflammatory stimuli. We determined that MYLK is alternatively spliced, yielding functionally distinct nmMLCK splice variants inclu...
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| Yayımlandı: | Am J Respir Cell Mol Biol |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Thoracic Society
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5248959/ https://ncbi.nlm.nih.gov/pubmed/27529643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0053OC |
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