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The human XPG gene: gene architecture, alternative splicing and single nucleotide polymorphisms

Defects in the XPG DNA repair endonuclease gene can result in the cancer-prone disorders xeroderma pigmentosum (XP) or the XP–Cockayne syndrome complex. While the XPG cDNA sequence was known, determination of the genomic sequence was required to understand its different functions. In cells from norm...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Emmert, Steffen, Schneider, Thomas D., Khan, Sikandar G., Kraemer, Kenneth H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC31292/
https://ncbi.nlm.nih.gov/pubmed/11266544
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