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HNRNPA1-mediated 3′ UTR length changes of HN1 contributes to cancer- and senescence-associated phenotypes

Cellular senescence has been regarded as a mechanism of tumor suppression. Studying the regulation of gene expression at various levels in cell senescence will shed light on cancer therapy. Alternative polyadenylation (APA) regulates gene expression by altering 3′ untranslated regions (3′ UTR) and p...

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書誌詳細
出版年:Aging (Albany NY)
主要な著者: Jia, Qi, Nie, Hongbo, Yu, Peng, Xie, Baiyun, Wang, Chenji, Yang, Fu, Wei, Gang, Ni, Ting
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660030/
https://ncbi.nlm.nih.gov/pubmed/31257225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102060
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