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HNRNPA1-mediated 3′ UTR length changes of HN1 contributes to cancer- and senescence-associated phenotypes

Cellular senescence has been regarded as a mechanism of tumor suppression. Studying the regulation of gene expression at various levels in cell senescence will shed light on cancer therapy. Alternative polyadenylation (APA) regulates gene expression by altering 3′ untranslated regions (3′ UTR) and p...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Jia, Qi, Nie, Hongbo, Yu, Peng, Xie, Baiyun, Wang, Chenji, Yang, Fu, Wei, Gang, Ni, Ting
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660030/
https://ncbi.nlm.nih.gov/pubmed/31257225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.102060
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