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Cysteine depletion targets leukemia stem cells through inhibition of electron transport complex II
We have previously demonstrated that oxidative phosphorylation is required for the survival of human leukemia stem cells (LSCs) from patients with acute myeloid leukemia (AML). More recently, we demonstrated that LSCs in patients with de novo AML rely on amino acid metabolism to drive oxidative phos...
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| Udgivet i: | Blood |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6659257/ https://ncbi.nlm.nih.gov/pubmed/31101624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019898114 |
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