Nalaganje...
Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells
We previously demonstrated that leukemia stem cells (LSCs) in de novo acute myeloid leukemia (AML) patients are selectively reliant on amino acid metabolism and that treatment with the combination of venetoclax and azacitidine (ven/aza) inhibits amino acid metabolism, leading to cell death. In contr...
Shranjeno v:
| izdano v: | Cell Stem Cell |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2020
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7655603/ https://ncbi.nlm.nih.gov/pubmed/32822582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.07.021 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|