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Sonic Hedgehog Is a Determinant of γδ T-Cell Differentiation in the Thymus
Here we investigate the function of Hedgehog (Hh) signaling in thymic γδ T-cell maturation and subset differentiation. Analysis of Hh mutants showed that Hh signaling promotes γδ T-cell development in the thymus and influences γδ T-cell effector subset distribution. Hh-mediated transcription in thym...
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| Pubblicato in: | Front Immunol |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6658896/ https://ncbi.nlm.nih.gov/pubmed/31379834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01629 |
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