Sonic Hedgehog regulates thymic epithelial cell differentiation

Sonic Hedgehog (Shh) is expressed in the thymus, where it regulates T cell development. Here we investigated the influence of Shh on thymic epithelial cell (TEC) development. Components of the Hedgehog (Hh) signalling pathway were expressed by TEC, and use of a Gli Binding Site-green fluorescence pr...

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Bibliographische Detailangaben
Veröffentlicht in:J Autoimmun
Hauptverfasser: Saldaña, José Ignacio, Solanki, Anisha, Lau, Ching-In, Sahni, Hemant, Ross, Susan, Furmanski, Anna L., Ono, Masahiro, Holländer, Georg, Crompton, Tessa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Academic Press 2016
Schlagworte:
Short Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4803023/
https://ncbi.nlm.nih.gov/pubmed/26778835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2015.12.004
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