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A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells

The recent availability of somatic haploid cell lines has provided a unique tool for genetic studies in mammals. However, the percentage of haploid cells rapidly decreases in these cell lines, which we recently showed is due to their overgrowth by diploid cells present in the cultures. Based on this...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Olbrich, Teresa, Vega-Sendino, Maria, Murga, Matilde, de Carcer, Guillermo, Malumbres, Marcos, Ortega, Sagrario, Ruiz, Sergio, Fernandez-Capetillo, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656781/
https://ncbi.nlm.nih.gov/pubmed/31315040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.06.060
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