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From Plk1 to Plk5: Functional evolution of polo-like kinases
Mammalian polo-like kinases (Plks) are characterized by the presence of an N-terminal protein kinase domain and a C-terminal polo-box domain (PBD) involved in substrate binding and regulation of kinase activity. Plk1-4 have traditionally been linked to cell cycle progression, genotoxic stress and, m...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3230524/ https://ncbi.nlm.nih.gov/pubmed/21654194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.14.16494 |
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