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A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells

The recent availability of somatic haploid cell lines has provided a unique tool for genetic studies in mammals. However, the percentage of haploid cells rapidly decreases in these cell lines, which we recently showed is due to their overgrowth by diploid cells present in the cultures. Based on this...

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Bibliografski detalji
Izdano u:Cell Rep
Glavni autori: Olbrich, Teresa, Vega-Sendino, Maria, Murga, Matilde, de Carcer, Guillermo, Malumbres, Marcos, Ortega, Sagrario, Ruiz, Sergio, Fernandez-Capetillo, Oscar
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656781/
https://ncbi.nlm.nih.gov/pubmed/31315040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.06.060
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