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A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells

The recent availability of somatic haploid cell lines has provided a unique tool for genetic studies in mammals. However, the percentage of haploid cells rapidly decreases in these cell lines, which we recently showed is due to their overgrowth by diploid cells present in the cultures. Based on this...

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Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Olbrich, Teresa, Vega-Sendino, Maria, Murga, Matilde, de Carcer, Guillermo, Malumbres, Marcos, Ortega, Sagrario, Ruiz, Sergio, Fernandez-Capetillo, Oscar
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656781/
https://ncbi.nlm.nih.gov/pubmed/31315040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.06.060
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