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A Chemical Screen Identifies Compounds Capable of Selecting for Haploidy in Mammalian Cells

The recent availability of somatic haploid cell lines has provided a unique tool for genetic studies in mammals. However, the percentage of haploid cells rapidly decreases in these cell lines, which we recently showed is due to their overgrowth by diploid cells present in the cultures. Based on this...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cell Rep
Κύριοι συγγραφείς: Olbrich, Teresa, Vega-Sendino, Maria, Murga, Matilde, de Carcer, Guillermo, Malumbres, Marcos, Ortega, Sagrario, Ruiz, Sergio, Fernandez-Capetillo, Oscar
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Cell Press 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656781/
https://ncbi.nlm.nih.gov/pubmed/31315040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.06.060
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