The splicing factor Sf3b1 regulates erythroid maturation and proliferation via TGFβ signaling in zebrafish

The spliceosomal component Splicing Factor 3B, subunit 1 (SF3B1) is one of the most prevalently mutated factors in the bone marrow failure disorder myelodysplastic syndrome. There is a strong clinical correlation between SF3B1 mutations and erythroid defects, such as refractory anemia with ringed si...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood Adv
Prif Awduron: De La Garza, Adriana, Cameron, Rosannah C., Gupta, Varun, Fraint, Ellen, Nik, Sara, Bowman, Teresa V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2019
Pynciau:
Hematopoiesis and Stem Cells
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650725/
https://ncbi.nlm.nih.gov/pubmed/31300417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018027714
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