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The splicing factor Sf3b1 regulates erythroid maturation and proliferation via TGFβ signaling in zebrafish
The spliceosomal component Splicing Factor 3B, subunit 1 (SF3B1) is one of the most prevalently mutated factors in the bone marrow failure disorder myelodysplastic syndrome. There is a strong clinical correlation between SF3B1 mutations and erythroid defects, such as refractory anemia with ringed si...
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| Pubblicato in: | Blood Adv |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6650725/ https://ncbi.nlm.nih.gov/pubmed/31300417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018027714 |
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