The Spliceosomal Component Sf3b1 is Essential for Hematopoietic Differentiation in Zebrafish

SF3B1 (Splicing factor 3b, subunit 1) is one of the most commonly mutated factors in myelodysplastic syndrome (MDS). Although the genetic correlation between SF3B1 mutations and MDS etiology are quite strong, no in vivo model currently exists to explore how SF3B1 loss alters blood cell development....

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Udgivet i:Exp Hematol
Main Authors: De La Garza, Adriana, Cameron, Rosannah C., Nik, Sara, Payne, Sara G., Bowman, Teresa V.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4992596/
https://ncbi.nlm.nih.gov/pubmed/27260753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.05.012
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