TGF-β inhibitors stimulate red blood cell production by enhancing self-renewal of BFU-E erythroid progenitors

Burst-forming unit erythroid progenitors (BFU-Es) are so named based on their ability to generate in methylcellulose culture large colonies of erythroid cells that consist of “bursts” of smaller erythroid colonies derived from the later colony-forming unit erythroid progenitor erythropoietin (Epo)–d...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Gao, Xiaofei, Lee, Hsiang-Ying, da Rocha, Edroaldo Lummertz, Zhang, Cheng, Lu, Yi-Fen, Li, Dandan, Feng, Yuxiong, Ezike, Jideofor, Elmes, Russell R., Barrasa, M. Inmaculada, Cahan, Patrick, Li, Hu, Daley, George Q., Lodish, Harvey F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146747/
https://ncbi.nlm.nih.gov/pubmed/27777239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-05-718320
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