GATA-1-Mediated Proliferation Arrest during Erythroid Maturation

Transcription factor GATA-1 is essential for erythroid and megakaryocytic maturation. GATA-1 mutations are associated with hematopoietic precursor proliferation and leukemogenesis, suggesting a role in cell cycle control. While numerous GATA-1 target genes specifying mature hematopoietic phenotypes...

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Autores principales: Rylski, Marcin, Welch, John J., Chen, Ying-Yu, Letting, Danielle L., Diehl, J. Alan, Chodosh, Lewis A., Blobel, Gerd A., Weiss, Mitchell J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC162202/
https://ncbi.nlm.nih.gov/pubmed/12832487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.14.5031-5042.2003
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