Inhibition of CBP-Mediated Protein Acetylation by the Ets Family Oncoprotein PU.1

Aberrant expression of PU.1 inhibits erythroid cell differentiation and contributes to the formation of murine erythroleukemias (MEL). The molecular mechanism by which this occurs is poorly understood. Here we show that PU.1 specifically and efficiently inhibits CBP-mediated acetylation of several n...

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Bibliografiske detaljer
Main Authors: Hong, Wei, Kim, Alexander Y., Ky, Sokun, Rakowski, Carrie, Seo, Sang-Beom, Chakravarti, Debabrata, Atchison, Michael, Blobel, Gerd A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133832/
https://ncbi.nlm.nih.gov/pubmed/11997509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.11.3729-3743.2002
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