Inhibition of CBP-Mediated Protein Acetylation by the Ets Family Oncoprotein PU.1

Aberrant expression of PU.1 inhibits erythroid cell differentiation and contributes to the formation of murine erythroleukemias (MEL). The molecular mechanism by which this occurs is poorly understood. Here we show that PU.1 specifically and efficiently inhibits CBP-mediated acetylation of several n...

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Detalhes bibliográficos
Main Authors: Hong, Wei, Kim, Alexander Y., Ky, Sokun, Rakowski, Carrie, Seo, Sang-Beom, Chakravarti, Debabrata, Atchison, Michael, Blobel, Gerd A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133832/
https://ncbi.nlm.nih.gov/pubmed/11997509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.11.3729-3743.2002
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