Inhibition of CBP-Mediated Protein Acetylation by the Ets Family Oncoprotein PU.1

Aberrant expression of PU.1 inhibits erythroid cell differentiation and contributes to the formation of murine erythroleukemias (MEL). The molecular mechanism by which this occurs is poorly understood. Here we show that PU.1 specifically and efficiently inhibits CBP-mediated acetylation of several n...

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Autores principales: Hong, Wei, Kim, Alexander Y., Ky, Sokun, Rakowski, Carrie, Seo, Sang-Beom, Chakravarti, Debabrata, Atchison, Michael, Blobel, Gerd A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Transcriptional Regulation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC133832/
https://ncbi.nlm.nih.gov/pubmed/11997509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.11.3729-3743.2002
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