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Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies

In cancer research, it remains challenging to functionally validate putative novel oncogenic drivers and to establish relevant preclinical models for evaluation of novel therapeutic strategies. Here, we describe an optimized and efficient pipeline for the generation of novel conditional overexpressi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Pieters, Tim, T’Sas, Sara, Demoen, Lisa, Almeida, André, Haenebalcke, Lieven, Matthijssens, Filip, Lemeire, Kelly, D’Hont, Jinke, Van Rockeghem, Frederique, Hochepied, Tino, Lintermans, Beatrice, Reunes, Lindy, Lammens, Tim, Berx, Geert, Haigh, Jody J., Goossens, Steven, Van Vlierberghe, Pieter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646380/
https://ncbi.nlm.nih.gov/pubmed/31332244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46853-x
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