Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies

In cancer research, it remains challenging to functionally validate putative novel oncogenic drivers and to establish relevant preclinical models for evaluation of novel therapeutic strategies. Here, we describe an optimized and efficient pipeline for the generation of novel conditional overexpressi...

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Publicado en:Sci Rep
Main Authors: Pieters, Tim, T’Sas, Sara, Demoen, Lisa, Almeida, André, Haenebalcke, Lieven, Matthijssens, Filip, Lemeire, Kelly, D’Hont, Jinke, Van Rockeghem, Frederique, Hochepied, Tino, Lintermans, Beatrice, Reunes, Lindy, Lammens, Tim, Berx, Geert, Haigh, Jody J., Goossens, Steven, Van Vlierberghe, Pieter
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646380/
https://ncbi.nlm.nih.gov/pubmed/31332244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46853-x
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