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ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms

ZEB1 and ZEB2 are structurally related E-box binding homeobox transcription factors that induce epithelial to mesenchymal transitions during development and disease. As such, they regulate cancer cell invasion, dissemination and metastasis of solid tumors. In addition, their expression is associated...

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Bibliografische gegevens
Gepubliceerd in:Haematologica
Hoofdauteurs: Goossens, Steven, Wang, Jueqiong, Tremblay, Cedric S., De Medts, Jelle, T’Sas, Sara, Nguyen, Thao, Saw, Jesslyn, Haigh, Katharina, Curtis, David J., Van Vlierberghe, Pieter, Berx, Geert, Taghon, Tom, Haigh, Jody J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ferrata Storti Foundation 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669144/
https://ncbi.nlm.nih.gov/pubmed/30679322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.207837
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