ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms

ZEB1 and ZEB2 are structurally related E-box binding homeobox transcription factors that induce epithelial to mesenchymal transitions during development and disease. As such, they regulate cancer cell invasion, dissemination and metastasis of solid tumors. In addition, their expression is associated...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Haematologica
Prif Awduron: Goossens, Steven, Wang, Jueqiong, Tremblay, Cedric S., De Medts, Jelle, T’Sas, Sara, Nguyen, Thao, Saw, Jesslyn, Haigh, Katharina, Curtis, David J., Van Vlierberghe, Pieter, Berx, Geert, Taghon, Tom, Haigh, Jody J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Ferrata Storti Foundation 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669144/
https://ncbi.nlm.nih.gov/pubmed/30679322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.207837
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