ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms

ZEB1 and ZEB2 are structurally related E-box binding homeobox transcription factors that induce epithelial to mesenchymal transitions during development and disease. As such, they regulate cancer cell invasion, dissemination and metastasis of solid tumors. In addition, their expression is associated...

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Publicado en:Haematologica
Autores principales: Goossens, Steven, Wang, Jueqiong, Tremblay, Cedric S., De Medts, Jelle, T’Sas, Sara, Nguyen, Thao, Saw, Jesslyn, Haigh, Katharina, Curtis, David J., Van Vlierberghe, Pieter, Berx, Geert, Taghon, Tom, Haigh, Jody J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Ferrata Storti Foundation 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669144/
https://ncbi.nlm.nih.gov/pubmed/30679322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.207837
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