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Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes

Deciphering molecular events required for full transformation of normal cells into cancer cells remains a challenge. In T-cell acute lymphoblastic leukemia (T-ALL), the genes encoding the TAL1/SCL and LMO1/2 transcription factors are recurring targets of chromosomal translocations, whereas NOTCH1 is...

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Detalhes bibliográficos
Main Authors: Tremblay, Mathieu, Tremblay, Cédric S., Herblot, Sabine, Aplan, Peter D., Hébert, Josée, Perreault, Claude, Hoang, Trang
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878648/
https://ncbi.nlm.nih.gov/pubmed/20516195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1897910
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