SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells

The molecular determinants that render specific populations of normal cells susceptible to oncogenic reprogramming into self-renewing cancer stem cells are poorly understood. Here, we exploit T-cell acute lymphoblastic leukemia (T-ALL) as a model to define the critical initiating events in this dise...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Gerby, Bastien, Tremblay, Cedric S., Tremblay, Mathieu, Rojas-Sutterlin, Shanti, Herblot, Sabine, Hébert, Josée, Sauvageau, Guy, Lemieux, Sébastien, Lécuyer, Eric, Veiga, Diogo F. T., Hoang, Trang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270438/
https://ncbi.nlm.nih.gov/pubmed/25522233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004768
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi