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SCL, LMO1 and Notch1 Reprogram Thymocytes into Self-Renewing Cells
The molecular determinants that render specific populations of normal cells susceptible to oncogenic reprogramming into self-renewing cancer stem cells are poorly understood. Here, we exploit T-cell acute lymphoblastic leukemia (T-ALL) as a model to define the critical initiating events in this dise...
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| Pubblicato in: | PLoS Genet |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4270438/ https://ncbi.nlm.nih.gov/pubmed/25522233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004768 |
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