Genetic interaction between Kit and Scl

SCL/TAL1, a tissue-specific transcription factor of the basic helix-loop-helix family, and c-Kit, a tyrosine kinase receptor, control hematopoietic stem cell survival and quiescence. Here we report that SCL levels are limiting for the clonal expansion of Kit(+) multipotent and erythroid progenitors....

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Bibliografski detalji
Glavni autori: Lacombe, Julie, Krosl, Gorazd, Tremblay, Mathieu, Gerby, Bastien, Martin, Richard, Aplan, Peter D., Lemieux, Sebastien, Hoang, Trang
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2013
Teme:
Hematopoiesis and Stem Cells
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952531/
https://ncbi.nlm.nih.gov/pubmed/23836559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-01-331819
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