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p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification
E-cadherin-mediated cell-cell adhesion is critical for naive pluripotency of cultured mouse embryonic stem cells (mESCs). E-cadherin-depleted mESC fail to downregulate their pluripotency program and are unable to initiate lineage commitment. To further explore the roles of cell adhesion molecules du...
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| Veröffentlicht in: | PLoS Genet |
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| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4996431/ https://ncbi.nlm.nih.gov/pubmed/27556156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006243 |
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