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Steroid Receptor/Coactivator Binding Inhibitors: An Update.

The purpose of this review is to highlight recent developments in small molecules and peptides that block the binding of coactivators to steroid receptors. These coactivator binding inhibitors bind at the coregulator binding groove, also known as Activation Function-2, rather than at the ligand-bind...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Endocrinol
Autori principali: Skowron, Kornelia J., Booker, Kenneth, Cheng, Changfeng, Creed, Simone, David, Brian P., Lazzara, Phillip R., Lian, Amy, Siddiqui, Zamia, Speltz, Thomas E., Moore, Terry W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6645384/
https://ncbi.nlm.nih.gov/pubmed/31163202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2019.110471
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