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A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction

We and others have proposed that coactivator binding inhibitors, which block the interaction of estrogen receptor and steroid receptor coactivators, may represent a potential class of new breast cancer therapeutics. The development of coactivator binding inhibitors has been limited, however, because...

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Detalles Bibliográficos
Publicado en:ACS Chem Biol
Main Authors: Speltz, Thomas E., Danes, Jeanne M., Stender, Joshua D., Frasor, Jonna M., Moore, Terry W.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057476/
https://ncbi.nlm.nih.gov/pubmed/29309722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b01016
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