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Estrogen down-regulation of the corepressor N-CoR: Mechanism and implications for estrogen derepression of N-CoR-regulated genes

The nuclear receptor corepressor N-CoR plays a crucial role in the repressive activity of diverse transcription factors, yet little is known about what regulates its cellular level. We have found that estrogen markedly down-regulates N-CoR protein levels in estrogen receptor (ER)-positive breast can...

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Autores principales: Frasor, Jonna, Danes, Jeanne M., Funk, Cory C., Katzenellenbogen, Benita S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201577/
https://ncbi.nlm.nih.gov/pubmed/16141343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502782102
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